Anything that doesn't need any translation does not need go go through Bome MIDI Translator Pro (MT Pro.) However if the same device has some things that need translation and others that don't, then you will need to go through Bome MIDI Translator Pro and use virtual ports with your Studio One application, breaking the existing direct connection.
Typically you would open MT Pro first so that it can connect directly to your device first, especially when running Windows which will not allow a second device to connect. Then your DAW should be able to connect to the Bome Virtual port(s) you may need.
Steve Caldwell
Bome Customer Care
Also available for paid consulting services: bome@sniz.biz